A Non-Human Primate Model for Gluten Sensitivity

A Non-Human Primate Model for Gluten Sensitivity

BACKGROUND AND AIMS Gluten sensitivity is widespread among humans. For example, in celiac disease patients, an inflammatory response to dietary gluten leads to enteropathy, malabsorption, circulating antibodies against gluten and transglutaminase 2, and clinical symptoms such as diarrhea. There is a growing need in fundamental and translational research for animal models that exhibit aspects of...

non coeliac gluten sensitivity

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Non-Celiac Gluten Sensitivity

[Non-celiac gluten sensitivity].

Non-celiac gluten sensitivity has recently been recognized by the scientific community as a part of gluten-related disorders, and is defined as a condition with gastrointestinal and/or extra-intestinal symptoms triggered by gluten ingestion in the absence of celiac disease and wheat allergy. Currently, there is no specific serological marker and non-celiac gluten sensitivity remains a diagnosis...

Non coeliac gluten sensitivity

In the past, the terms gluten sensitivity and coeliac disease have been used synonymously but this is not acceptable since gluten sensitivity can occur in subjects who do not have coeliac disease. The entity of non coeliac gluten intolerance has been regarded as a new diagnosis (1) but it is better to consider it an old diagnosis recently rediscovered and embellished. In the late 1970s brief ca...